Nefroosne nefrootiline diabeet

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The earliest clinical evidence of nephropathy is the appearance of low but abnormal levels (≥ 30 mg/day or 20 μg/min) of albumin in the urine, referred to as microalbuminuria, and patients with microalbuminuria are referred to as having incipient nephropathy. Without specific interventions, ∼80.

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Nephrotic syndrome is defined as urine total protein 3.5 g/d or total protein-creatinine ratio of 3.5 g/g, low serum albumin, high serum cholesterol, and peripheral edema. These threshold levels have not been rigorously evaluated in diabetic kidney disease or using urine albumin, the preferred measure of proteinuria in diabetes.
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Diabetic nephropathy (DN), also known as diabetic kidney disease, is the chronic loss of kidney function occurring in those with diabetes mellitus. Protein loss in the urine due to damage to the glomeruli may become massive, and cause a low serum albumin with resulting generalized body swelling (edema) and result in the nephrotic syndrome.
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Each kidney is made of hundreds of thousands of small units called nephrons. These structures filter your blood, help remove waste from the body, and control fluid balance. In people with diabetes, the nephrons slowly thicken and become scarred over time. The nephrons begin to leak, and protein.
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PROTEINURIA MIL GRACIAS A TODOS POR ESTA ROTACIÓN Soldatos G, Cooper ME. Diabetic nephropathy: important pathophysiologic mechanisms. Diabetes Res Clin Pract 2008 Nov 13;82 Suppl 1:S75-9.




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