Kandiasis diabeediga meestel

Temozolomide (TMZ) is an alkylating agent primarily used to treat tumors of the central nervous system. We describe 2 patients with apparent TMZ-induced central diabetes insipidus. Using our institution s Research Patient Database Registry, we identified 3 additional potential cases of TMZ-induced.

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Blockade of KCa3.1 reversed diabetes-induced upregulation of LC3 expression in kidney proximal tubules of diabetic mice. To further determine the role of KCa3.1 in regulating tubular autophagy in diabetic kidneys, autophagy marker LC3 expression was assessed in the kidneys of diabetic animals using confocal microscopy.

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Kandiasis diabeediga meestel:

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